Safety of Redo Hepatectomy for Colorectal Liver Metastases after Selective Interarterial Radiation Therapy: A Case Report

Surgical resection is the only potentially curative strategy in the treatment of patients with colorectal liver metastases (CLM). Unfortunately, only about 10%–15% of patients are candidates for resection. Preoperative chemotherapy aims to increase the number of patients that may be eligible for liv...

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Main Authors: Kyriakos Neofytou, Harpreet Wasan, Satvinder Mudan
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2014/712572
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spelling doaj-517746c2040d4f49967daee422bcb0a72020-11-25T00:37:37ZengHindawi LimitedCase Reports in Surgery2090-69002090-69192014-01-01201410.1155/2014/712572712572Safety of Redo Hepatectomy for Colorectal Liver Metastases after Selective Interarterial Radiation Therapy: A Case ReportKyriakos Neofytou0Harpreet Wasan1Satvinder Mudan2Royal Marsden Hospital, Department of Academic Surgery, Upper GI/HPB Unit, Fulham Road, London SW3 6JJ, UKOncology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London W12 0HS, UKRoyal Marsden Hospital, Department of Academic Surgery, Upper GI/HPB Unit, Fulham Road, London SW3 6JJ, UKSurgical resection is the only potentially curative strategy in the treatment of patients with colorectal liver metastases (CLM). Unfortunately, only about 10%–15% of patients are candidates for resection. Preoperative chemotherapy aims to increase the number of patients that may be eligible for liver resection by downsizing liver metastases. For patients with unresectable, chemotherapy refractory CLM the available treatment options are limited. Selective interarterial radiation therapy (SIRT) is one of the most promising treatment options for this group of patients. Although only a small number of these patients have been reported as becoming candidates for potentially curative hepatic resection following sufficient reduction in the volume of liver metastases, the question arises regarding the safety of liver resection in these patients. We report a case of a patient who presented unresectable liver relapse of CLM after previous right hepatectomy. He underwent SIRT which resulted in downsizing of the liver metastases making the patient candidate for left lateral sectionectomy. He underwent the redo hepatectomy without any complications. To the best of our knowledge, this is the first reported case of redo hepatectomy after SIRT for CLM.http://dx.doi.org/10.1155/2014/712572
collection DOAJ
language English
format Article
sources DOAJ
author Kyriakos Neofytou
Harpreet Wasan
Satvinder Mudan
spellingShingle Kyriakos Neofytou
Harpreet Wasan
Satvinder Mudan
Safety of Redo Hepatectomy for Colorectal Liver Metastases after Selective Interarterial Radiation Therapy: A Case Report
Case Reports in Surgery
author_facet Kyriakos Neofytou
Harpreet Wasan
Satvinder Mudan
author_sort Kyriakos Neofytou
title Safety of Redo Hepatectomy for Colorectal Liver Metastases after Selective Interarterial Radiation Therapy: A Case Report
title_short Safety of Redo Hepatectomy for Colorectal Liver Metastases after Selective Interarterial Radiation Therapy: A Case Report
title_full Safety of Redo Hepatectomy for Colorectal Liver Metastases after Selective Interarterial Radiation Therapy: A Case Report
title_fullStr Safety of Redo Hepatectomy for Colorectal Liver Metastases after Selective Interarterial Radiation Therapy: A Case Report
title_full_unstemmed Safety of Redo Hepatectomy for Colorectal Liver Metastases after Selective Interarterial Radiation Therapy: A Case Report
title_sort safety of redo hepatectomy for colorectal liver metastases after selective interarterial radiation therapy: a case report
publisher Hindawi Limited
series Case Reports in Surgery
issn 2090-6900
2090-6919
publishDate 2014-01-01
description Surgical resection is the only potentially curative strategy in the treatment of patients with colorectal liver metastases (CLM). Unfortunately, only about 10%–15% of patients are candidates for resection. Preoperative chemotherapy aims to increase the number of patients that may be eligible for liver resection by downsizing liver metastases. For patients with unresectable, chemotherapy refractory CLM the available treatment options are limited. Selective interarterial radiation therapy (SIRT) is one of the most promising treatment options for this group of patients. Although only a small number of these patients have been reported as becoming candidates for potentially curative hepatic resection following sufficient reduction in the volume of liver metastases, the question arises regarding the safety of liver resection in these patients. We report a case of a patient who presented unresectable liver relapse of CLM after previous right hepatectomy. He underwent SIRT which resulted in downsizing of the liver metastases making the patient candidate for left lateral sectionectomy. He underwent the redo hepatectomy without any complications. To the best of our knowledge, this is the first reported case of redo hepatectomy after SIRT for CLM.
url http://dx.doi.org/10.1155/2014/712572
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AT harpreetwasan safetyofredohepatectomyforcolorectallivermetastasesafterselectiveinterarterialradiationtherapyacasereport
AT satvindermudan safetyofredohepatectomyforcolorectallivermetastasesafterselectiveinterarterialradiationtherapyacasereport
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