High Expression of Lysophosphatidic Acid Induces Nerve Injury in LSS Patients via AKT Mediated NF-κB p65 Pathway

High Expression of Lysophosphatidic Acid Induces Nerve Injury in LSS Patients via AKT Mediated NF-κB p65 Pathway

Lumbar spinal stenosis (LSS) is a spinal degenerative disease, complicated with nerve injury. Lysophosphatidic acid (LPA), a kind of glycerophospholipid molecule is elevated in the initial stages of neural injury. This research aimed to investigate the patho-mechanism of nerve injury caused by LPA i...

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Bibliographic Details
Main Authors: Guiliang Zhai, Wenfei Liang, Yongjun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
lumbar spinal stenosis
lysophosphatidic acid
Akt
NF-κB pathway 3
LSS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.641435/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.641435/full

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