Glomerular galactose-deficient IgA1 expression analysis in pediatric patients with glomerular diseases

Glomerular galactose-deficient IgA1 expression analysis in pediatric patients with glomerular diseases

Abstract Galactose-deficient IgA1 (Gd-IgA1) is important in the pathogenesis of IgA nephropathy (IgAN). A Gd-IgA1-specific monoclonal antibody (KM55) has revealed glomerular Gd-IgA1 deposition solely in patients with IgAN and IgA vasculitis with nephritis (IgAV-N). However, this specificity is contr...

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Bibliographic Details
Main Authors: Shinya Ishiko, Tomoko Horinouchi, Rika Fujimaru, Yuko Shima, Hiroshi Kaito, Ryojiro Tanaka, Shingo Ishimori, Atsushi Kondo, Sadayuki Nagai, Yuya Aoto, Nana Sakakibara, China Nagano, Tomohiko Yamamura, Momoka Yoshimura, Koichi Nakanishi, Junya Fujimura, Naohiro Kamiyoshi, Hiroaki Nagase, Norishige Yoshikawa, Kazumoto Iijima, Kandai Nozu
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-71101-y

Internet

https://doi.org/10.1038/s41598-020-71101-y

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