Targeting hypoxia in tumor: a new promising therapeutic strategy
Abstract Low oxygen condition (hypoxia) is considered a hallmark of rapidly growing solid tumors. The presence of hypoxia renders tumor cells resistant to conventional chemo- and radio-therapy, selecting a more malignant and invasive phenotype and playing a negative role in patient prognosis. This c...
Main Authors: | Maria Carla Bosco, Gabriella D’Orazi, Donatella Del Bufalo |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13046-019-1517-0 |
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