Spontaneous splenic rupture in a teenager as first manifestation of acute myeloid leukemia: Case report and literature review

Spontaneous splenic rupture is a well-known, but rare life-threatening complication of hematological malignancies. We describe the case of a 12-year-old boy with a 5-day history of fever and successively left upper quadrant abdominal pain and sudden clinical deterioration necessitating emergency spl...

Full description

Bibliographic Details
Main Authors: Antonio Villa, Simona Rossi, Isabella Riva, Cecilia Tedesco, Francesca Maria Zanchettin, Rinaldo Chiumento
Format: Article
Language:English
Published: Edizioni FS 2018-11-01
Series:Journal of Health and Social Sciences
Subjects:
Online Access:https://journalhss.com/wp-content/uploads/jhss33_297-302.pdf
Description
Summary:Spontaneous splenic rupture is a well-known, but rare life-threatening complication of hematological malignancies. We describe the case of a 12-year-old boy with a 5-day history of fever and successively left upper quadrant abdominal pain and sudden clinical deterioration necessitating emergency splenectomy. On arrival, a blood dyscrasia was postoperatively confirmed as acute myeloid leukemia. Cases of atraumatic rupture in diseased spleens are widely reported and pathological rupture of the spleen is a rare, but well recognized complication in hematological malignancies. This case report represents a rare and fatal initial presentation of acute myeloid leukemia in an adolescent. Because of the rarity of atraumatic splenic rupture, a high index of clinical suspicion must be maintained in patients with left upper quadrant pain and abnormal differential count on peripheral blood smear.
ISSN:2499-2240
2499-5886