Fibroblasts Colonizing Nerve Conduits Express High Levels of Soluble Neuregulin1, a Factor Promoting Schwann Cell Dedifferentiation

Fibroblasts Colonizing Nerve Conduits Express High Levels of Soluble Neuregulin1, a Factor Promoting Schwann Cell Dedifferentiation

Conduits for the repair of peripheral nerve gaps are a good alternative to autografts as they provide a protected environment and a physical guide for axonal re-growth. Conduits require colonization by cells involved in nerve regeneration (Schwann cells, fibroblasts, endothelial cells, macrophages)...

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Bibliographic Details
Main Authors: Benedetta E. Fornasari, Marwa El Soury, Giulia Nato, Alessia Fucini, Giacomo Carta, Giulia Ronchi, Alessandro Crosio, Isabelle Perroteau, Stefano Geuna, Stefania Raimondo, Giovanna Gambarotta
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
Neuregulin 1
nerve fibroblasts
nerve regeneration
Schwann cells
nerve guide
chitosan
Online Access:https://www.mdpi.com/2073-4409/9/6/1366

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