LC-HRMS Screening and Identification of Novel Peptide Markers of Ricin Based on Multiple Protease Digestion Strategies

LC-HRMS Screening and Identification of Novel Peptide Markers of Ricin Based on Multiple Protease Digestion Strategies

Both ricin and <i>R. communis</i> <i>agglutinin</i> (RCA120), belonging to the type II ribosome-inactivating proteins (RIPs-Ⅱ), are derived from the seeds of the castor bean plant. They share very similar amino acid sequences, but ricin is much more toxic than RCA120. It is u...

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Bibliographic Details
Main Authors: Long-Hui Liang, Chang-Cai Liu, Bo Chen, Long Yan, Hui-Lan Yu, Yang Yang, Ji-Na Wu, Xiao-Sen Li, Shi-Lei Liu
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Toxins
Subjects:
ricin
marker peptides
unambiguous identification
mass spectrometry
Online Access:https://www.mdpi.com/2072-6651/11/7/393

Internet

https://www.mdpi.com/2072-6651/11/7/393

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