Acute effects of hypouricemia on endothelium, oxidative stress, and arterial stiffness: A randomized, double‐blind, crossover study

Acute effects of hypouricemia on endothelium, oxidative stress, and arterial stiffness: A randomized, double‐blind, crossover study

Abstract We hypothesized acute moderate and drastic reductions in uric acid concentration exert different effects on arterial function in healthy normotensive and hypertensive adults. Thirty‐six adults (aged 58 [55;63] years) with or without primary hypertension participated in a three‐way, randomiz...

Full description

Bibliographic Details
Main Authors: Benjamin De Becker, Emeline Hupkens, Laurence Dewachter, Catherine Coremans, Cédric Delporte, Pierre van Antwerpen, Thierry Franck, Karim Zouaoui Boudjeltia, Pierre Cullus, Philippe van deBorne
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Physiological Reports
Subjects:
febuxostat
NO synthase
rasburicase
renin–angiotensin–aldosterone system
Online Access:https://doi.org/10.14814/phy2.15018

Internet

https://doi.org/10.14814/phy2.15018

Similar Items