FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer

FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer

Abstract Background The role of cancer cell FOXP3 in tumorigenesis is conflicting. We aimed to study FOXP3 expression and regulation, function and clinical implication in human non-small cell lung cancer (NSCLC). Methods One hundred and six patients with histologically-confirmed NSCLC who underwent...

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Bibliographic Details
Main Authors: Shucai Yang, Yi Liu, Ming-Yue Li, Calvin S. H. Ng, Sheng-li Yang, Shanshan Wang, Chang Zou, Yujuan Dong, Jing Du, Xiang Long, Li-Zhong Liu, Innes Y. P. Wan, Tony Mok, Malcolm J. Underwood, George G. Chen
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Molecular Cancer
Subjects:
NSCLC
FOXP3
EMT
Wnt
TCF4
Online Access:http://link.springer.com/article/10.1186/s12943-017-0700-1

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http://link.springer.com/article/10.1186/s12943-017-0700-1

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