Targeting Insulin-Like Growth Factor-1 Signaling into the Central Nervous System for Promoting Myelin Repair

Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system (CNS). Without myelin, nerve impulses in the CNS are slowed or stopped, leading to a constellation of neurological symptoms. Demyelination also provides a permitting condition for irreversible axonal damag...

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Bibliographic Details
Main Authors: Nadine Wilczak, Jacques De Keyser, Daniel Chesik
Format: Article
Language:English
Published: AboutScience Srl 2008-01-01
Series:Drug Target Insights
Online Access:https://doi.org/10.4137/DTI.S362