Assessment of the accuracy of multi-parametric MRI with PI-RADS 2.0 scoring system in the discrimination of

• Main Authors: Hoda A. El-Kareem A. El-Samei, Mohamed Farghaly Amin, Ebtesam Esmail Hassan
• Format: Article
• Language: English
• Published: SpringerOpen 2016-09-01
• Series: The Egyptian Journal of Radiology and Nuclear Medicine
• Subjects: Mp-MRI prostate; PI-RAD2.0 score; Prostate focal lesions
• Online Access: http://www.sciencedirect.com/science/article/pii/S0378603X16300596

Objectives: Assessing the value of Mp-MRI with PI-RAD2.0 in distinguishing between malignant and benign prostatic lesions. Patients & methods: 55 patients with suspicious prostatic lesions underwent PR examination, PSA tests, TRU/S, and Mp-MRI prostate. Mean age was 62 years and imaging data were correlated with histopathological data. Results: Histopathology results revealed 38 malignant lesions and 17 were benign. DWI showed significant restriction with low ADC value, 0.89 ± 0.24 μm2/ms in 30 PZ lesions that diagnosed to be likely malignant, (3–5 score) and 7 benign lesions showed no diffusion abnormality with ADC values, 1.34 ± 0.21 μm2/ms which were statistically significantly higher than those of malignant lesions (P < 0.001). Of the 18 TZ lesions, T2 WI diagnosed 7 to be likely malignant (score 3–5) and 11 were benign (1–2 score). DCE-MRI revealed positive results in 28 PZ and 8 TZ lesions. Adding DCE-MRI to DWI and T2WI score in equivocal lesions raises its score from 3 to 4 in 6/9 lesions that aid in malignant lesions diagnosis. Negative enhancement was noted in 9 PZ and 10 TZ benign lesions (−ve). Conclusion: Multi-parametric MRI with PI-RAD V2 scoring system was proved to be non invasive and accurate tool for distinguishing between malignant and benign prostatic lesions.