RANKL-Induced Btn2a2 – A T Cell Immunomodulatory Molecule – During Osteoclast Differentiation Fine-Tunes Bone Resorption

RANKL-Induced Btn2a2 – A T Cell Immunomodulatory Molecule – During Osteoclast Differentiation Fine-Tunes Bone Resorption

Butyrophilins, which are members of the extended B7 family of immunoregulators structurally related to the B7 family, have diverse functions on immune cells as co-stimulatory and co-inhibitory molecules. Despite recent advances in the understanding on butyrophilins’ role on adaptive immune cells dur...

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Bibliographic Details
Main Authors: Michael Frech, Gregor Schuster, Fabian T. Andes, Georg Schett, Mario M. Zaiss, Kerstin Sarter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Endocrinology
Subjects:
osteoclast (OC)
RANKL (receptor activator for nuclear factor k B ligand)
bone homeostasis
bone resorption
T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.685060/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.685060/full

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