Computational Drug Screening Identifies Compounds Targeting Renal Age-associated Molecular Profiles

Aging is a major driver for chronic kidney disease (CKD) and the counterbalancing of aging processes holds promise to positively impact disease development and progression.In this study we generated a signature of renal age-associated genes (RAAGs) based on six different data sources including trans...

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Bibliographic Details
Main Authors: Christian Koppelstaetter, Johannes Leierer, Michael Rudnicki, Julia Kerschbaum, Andreas Kronbichler, Anette Melk, Gert Mayer, Paul Perco
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037019301679