Interplay of Biochemical, Genetic, and Immunohistochemical Factors in the Etio-Pathogenesis of Gastric Ulcer in Rats: A Comparative Study of the Effect of Pomegranate Loaded Nanoparticles Versus Pomegranate Peel Extract

Interplay of Biochemical, Genetic, and Immunohistochemical Factors in the Etio-Pathogenesis of Gastric Ulcer in Rats: A Comparative Study of the Effect of Pomegranate Loaded Nanoparticles Versus Pomegranate Peel Extract

BackgroundFew data are available about the role of herbal extract loaded nanoparticles as an alternative safe medicine for the management of a gastric ulcer.AimThis work is targeted at exploring the physiological effects of pomegranate loaded nanoparticles (PLN) against an indomethacin IND-induced g...

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Main Authors: Nessren M. Abd el-Rady, Marwa A. Dahpy, Amel Ahmed, Dalia A. Elgamal, Safy Hadiya, Mai A. M. Ahmed, Zain El-Abdeen Ahmed Sayed, Doaa Abdeltawab, Ahmed Shawkat Abdelmohsen, Alshaimaa Abdelkhaliq Mohammad Farrag, Ahmed M. Ashmawy, Marwa K. Khairallah, Heba M. Galal
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
IND-induced gastric ulcer
pomegranate loaded nanoparticles
nitric oxide
TAC
TNF-α
PGE2
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.649462/full

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