Functional Assessment of Intrahypothalamic Implants of Immortalized Gonadotropin-Releasing Hormone-Secreting Cells in Female Hypogonadal Mice

The hypogonadal (HPG) mouse is a mutant that lacks a functional gonadotropin-releasing hormone (GnRH) gene. In this study, female HPG mice received bilateral intrahypothalamic implants of an immortalized GnRH-secreting cell line (GT1-7). Nine mice were tested 42-65 days after implantation to determi...

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Bibliographic Details
Main Authors: Gregory M. Miller, Ann-Judith Silverman, James L. Roberts, Ke Wen Dong, Marie J. Gibson
Format: Article
Language:English
Published: SAGE Publishing 1993-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979300200309