The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases

AbstractThe systemic and organ‐specific human fibrotic disorders collectively represent one of the most serious health problems world‐wide causing a large proportion of the total world population mortality. The molecular pathways involved in their pathogenesis are complex and despite intensive inves...

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Bibliographic Details
Main Authors: Peter J Wermuth, Sergio A Jimenez
Format: Article
Language:English
Published: Wiley 2015-12-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s40169-015-0047-4