Estimation of affinities of ligands in mixtures <it>via </it>magnetic recovery of target-ligand complexes and chromatographic analyses: chemometrics and an experimental model

<p>Abstract</p> <p>Background</p> <p>The combinatorial library strategy of using multiple candidate ligands in mixtures as library members is ideal in terms of cost and efficiency, but needs special screening methods to estimate the affinities of candidate ligands in su...

Full description

Bibliographic Details
Main Authors: Yuan Huidong, Zhang Chun, Long Gaobo, Zhu Sha, Yuan Yonghua, Liao Juan, Zhao Hua, Pu Jun, Xie Yanling, Yang Xiaolan, Chen Yiwen, Liao Fei
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/44