Informative noncompliance in endpoint trials

<p>Abstract</p> <p>Noncompliance with study medications is an important issue in the design of endpoint clinical trials. Including noncompliant patient data in an intention-to-treat analysis could seriously decrease study power. Standard methods for calculating sample size account...

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Bibliographic Details
Main Authors: Iglewicz Boris, Jiang Qi, Snapinn Steven M
Format: Article
Language:English
Published: BMC 2004-07-01
Series:Current Controlled Trials in Cardiovascular Medicine
Online Access:http://cvm.controlled-trials.com/content/5/1/5

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