Regulation of Angiogenesis Discriminates Tissue Resident MSCs from Effective and Defective Osteogenic Environments

Regulation of Angiogenesis Discriminates Tissue Resident MSCs from Effective and Defective Osteogenic Environments

Background: The biological mechanisms that contribute to atrophic long bone non-union are poorly understood. Multipotential mesenchymal stromal cells (MSCs) are key contributors to bone formation and are recognised as important mediators of blood vessel formation. This study examines the role of MSC...

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Bibliographic Details
Main Authors: R. J. Cuthbert, E. Jones, C. Sanjurjo-Rodríguez, A. Lotfy, P. Ganguly, S. M. Churchman, P. Castana, H. B. Tan, D. McGonagle, E. Papadimitriou, P. V. Giannoudis
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Journal of Clinical Medicine
Subjects:
MSCs
fracture healing
non-union
induced periosteum
osteogenesis
regenerative medicine
Online Access:https://www.mdpi.com/2077-0383/9/6/1628

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https://www.mdpi.com/2077-0383/9/6/1628

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