The Diverse Calpain Family in Trypanosomatidae: Functional Proteins Devoid of Proteolytic Activity?

The Diverse Calpain Family in Trypanosomatidae: Functional Proteins Devoid of Proteolytic Activity?

Calpains are calcium-dependent cysteine peptidases that were originally described in mammals and, thereafter, their homologues were identified in almost all known living organisms. The deregulated activity of these peptidases is associated with several pathologies and, consequently, huge efforts hav...

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Bibliographic Details
Main Authors: Vítor Ennes-Vidal, Marta Helena Branquinha, André Luis Souza dos Santos, Claudia Masini d’Avila-Levy
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
cysteine peptidase
<i>Trypanosoma</i>
<i>Leishmania</i>
chemotherapy
Online Access:https://www.mdpi.com/2073-4409/10/2/299

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