The potential of CRISPR/Cas9 genome editing for the study and treatment of intervertebral disc pathologies

The potential of CRISPR/Cas9 genome editing for the study and treatment of intervertebral disc pathologies

The CRISPR/Cas9 system has emerged as a powerful tool for mammalian genome engineering. In basic and translational intervertebral disc (IVD) research, this technique has remarkable potential to answer fundamental questions on pathway interactions, to simulate IVD pathologies, and to promote drug dev...

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Bibliographic Details
Main Authors: Olga Krupkova, Elena Cambria, Lenka Besse, Andrej Besse, Robert Bowles, Karin Wuertz‐Kozak
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:JOR Spine
Subjects:
CRISPR/Cas9
degenerative disc disease
intervertebral disc
low back pain
targeted genome engineering
Online Access:https://doi.org/10.1002/jsp2.1003

Internet

https://doi.org/10.1002/jsp2.1003

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