STUDENT RESEARCH COMMITTEE , SCHOOL OF MEDICINE, SHIRAZ UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, SHIRAZ, IRAN

• Main Authors: MOSALAEI MAHNAZ, TAVAKOLI ABD ALREZA, GA REIS JALALI, S.A MALEK HOSSEINI
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2002-06-01
• Series: Journal of Research in Medical Sciences
• Subjects: Diabetic Nephropathy, Diabetes, Renal Transplantation
• Online Access: http://journals.mui.ac.ir/jrms/article/view/3257

Introduction. This study was performed to evaluate complications after transplantation and to compare result of transplantation in diabetic patinets and non-diabetic patients.
 Methods. In this study, medical records of all patients with diabetic nephropathy undergone this procedure from 1987 to 2000 in Namazi hospital (Shiraz, Iran) in 5 years of follow-up were reviewed (n = 50), and one hundred of non-diabetic patients in this center were chosen as control group. We matched both groups with regard to sex, age, and type of donor and year of transplantation. In order to evaluate both groups, we made a criteria with regard to post operation omplications, serum creatinine flactuations and 5 years follow up remarks and according to this ceiteria we divided patients into good, moderate and poor prognosis.
 Results. Mean age was 49 ± 9 (Mean ± SD) years in diabetic patients and 51±11.05 in non-diabetic patients. Retinopathy (23.1%) and Cardiovascular diseases (30.8%) were the most prevalent complication in diabetic patients. Serum creatinine flactuations showed more acceptable in non-diabetics during 5 years, but the average was the same after 5 years in both groups. (Mean serum crateanine=2). In contrast to other studies, post operation evaluation difference between both groups was statistically significant (P < 0.0001), it means that non-diabetics had better results in renal transplantation.
 Discussion .As diabetic nephropathy usually occurs many years after the onset of diabetes, renal transplantation should be preserved for patients with relatively less complication of diabetes.