Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0
The increasing discoveries regarding the biology and functions of platelets in the last decade undoubtedly show that these cells are one of the most biotechnological human cells. This review summarizes new advances in platelet biology, functions, and new concepts of biotech-educated platelets that c...
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MDPI AG
2020-08-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/21/17/6061 |
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doaj-5103f9ade96a41ecad14e02004a9d2b92020-11-25T03:47:00ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-08-01216061606110.3390/ijms21176061Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0Sheila Siqueira Andrade0Alessandra Valéria de Sousa Faria1Manoel João Batista C. Girão2Gwenny M. Fuhler3Maikel P. Peppelenbosch4Carmen V. Ferreira-Halder5PlateInnove Biotechnology, Piracicaba, SP 13414-018, BrazilDepartment of Biochemistry and Tissue Biology, University of Campinas, UNICAMP, Campinas, SP 13083-862, BrazilDepartment of Gynecology, Federal University of São Paulo, UNIFESP, São Paulo, SP 04024-002, BrazilDepartment of Gastroenterology and Hepatology Medical Center Rotterdam, NL-3000 CA Rotterdam, The NetherlandsDepartment of Gastroenterology and Hepatology Medical Center Rotterdam, NL-3000 CA Rotterdam, The NetherlandsDepartment of Biochemistry and Tissue Biology, University of Campinas, UNICAMP, Campinas, SP 13083-862, BrazilThe increasing discoveries regarding the biology and functions of platelets in the last decade undoubtedly show that these cells are one of the most biotechnological human cells. This review summarizes new advances in platelet biology, functions, and new concepts of biotech-educated platelets that connect advanced biomimetic science to platelet-based additive manufacturing for tissue regeneration. As highly responsive and secretory cells, platelets could be explored to develop solutions that alter injured microenvironments through platelet-based synthetic biomaterials with instructive extracellular cues for morphogenesis in tissue engineering beyond tissue regeneration 2.0.https://www.mdpi.com/1422-0067/21/17/6061plateletsbiotechnologytissue regenerationbiomaterialsgrowth factors |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Sheila Siqueira Andrade Alessandra Valéria de Sousa Faria Manoel João Batista C. Girão Gwenny M. Fuhler Maikel P. Peppelenbosch Carmen V. Ferreira-Halder |
| spellingShingle |
Sheila Siqueira Andrade Alessandra Valéria de Sousa Faria Manoel João Batista C. Girão Gwenny M. Fuhler Maikel P. Peppelenbosch Carmen V. Ferreira-Halder Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0 International Journal of Molecular Sciences platelets biotechnology tissue regeneration biomaterials growth factors |
| author_facet |
Sheila Siqueira Andrade Alessandra Valéria de Sousa Faria Manoel João Batista C. Girão Gwenny M. Fuhler Maikel P. Peppelenbosch Carmen V. Ferreira-Halder |
| author_sort |
Sheila Siqueira Andrade |
| title |
Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0 |
| title_short |
Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0 |
| title_full |
Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0 |
| title_fullStr |
Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0 |
| title_full_unstemmed |
Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0 |
| title_sort |
biotech-educated platelets: beyond tissue regeneration 2.0 |
| publisher |
MDPI AG |
| series |
International Journal of Molecular Sciences |
| issn |
1661-6596 1422-0067 |
| publishDate |
2020-08-01 |
| description |
The increasing discoveries regarding the biology and functions of platelets in the last decade undoubtedly show that these cells are one of the most biotechnological human cells. This review summarizes new advances in platelet biology, functions, and new concepts of biotech-educated platelets that connect advanced biomimetic science to platelet-based additive manufacturing for tissue regeneration. As highly responsive and secretory cells, platelets could be explored to develop solutions that alter injured microenvironments through platelet-based synthetic biomaterials with instructive extracellular cues for morphogenesis in tissue engineering beyond tissue regeneration 2.0. |
| topic |
platelets biotechnology tissue regeneration biomaterials growth factors |
| url |
https://www.mdpi.com/1422-0067/21/17/6061 |
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AT sheilasiqueiraandrade biotecheducatedplateletsbeyondtissueregeneration20 AT alessandravaleriadesousafaria biotecheducatedplateletsbeyondtissueregeneration20 AT manoeljoaobatistacgirao biotecheducatedplateletsbeyondtissueregeneration20 AT gwennymfuhler biotecheducatedplateletsbeyondtissueregeneration20 AT maikelppeppelenbosch biotecheducatedplateletsbeyondtissueregeneration20 AT carmenvferreirahalder biotecheducatedplateletsbeyondtissueregeneration20 |
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