Induction of MRSA Biofilm by Low-Dose β-Lactam Antibiotics: Specificity, Prevalence and Dose-Response Effects

Induction of MRSA Biofilm by Low-Dose β-Lactam Antibiotics: Specificity, Prevalence and Dose-Response Effects

Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of hospital- and community-associated infections. The formation of adherent clusters of cells known as biofilms is an important virulence factor in MRSA pathogenesis. Previous studies showed that subminimal inhibitory (sub-MIC) co...

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Bibliographic Details
Main Authors: Mandy Ng, Samuel B. Epstein, Mary T. Callahan, Brian O. Piotrowski, Gary L. Simon, Afsoon D. Roberts, John F. Keiser, Jeffrey B. Kaplan
Format: Article
Language:English
Published: SAGE Publishing 2014-01-01
Series:Dose-Response
Online Access:https://doi.org/10.2203/dose-response.13-021.Kaplan

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