Tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis

Tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis

Background and aims: Although the participation of cytokines in the pathogenesis of rheumatoid arthritis (RA) seems to be unequivocal, their relationship with current serum markers of this disease is not clear. The present study analyses whether there is any correlation between the levels of tumour...

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Main Authors: Tânia Silvia Fröde, Patrícia Tenconi, Marilei Reynaud Debiasi, Yara Santos Medeiros
Format: Article
Language:English
Published: Hindawi Limited 2002-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/0962935021000051539
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spelling doaj-50fb54d9720a4a4e929a7cfc2e26d79c2020-11-24T21:11:43ZengHindawi LimitedMediators of Inflammation0962-93511466-18612002-01-0111634534910.1080/0962935021000051539Tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritisTânia Silvia Fröde0Patrícia Tenconi1Marilei Reynaud Debiasi2Yara Santos Medeiros3Department of Clinical Analysis, Center of Healthy Sciences, Universidade Federal de Santa Catarina, Campus Universitário – Trindade, Florianópolis 88040–970, SC, BrazilLaboratório Médico Santa Luzia, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário – Trindade, Florianópolis 88040–970, SC, BrazilLaboratório Médico Santa Luzia, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário – Trindade, Florianópolis 88040–970, SC, BrazilDepartment of Pharmacology, Center of Biological Sciences, Universidade Federal de Santa Catarina, Campus Universitário – Trindade, Florianópolis 88040–970, SC, BrazilBackground and aims: Although the participation of cytokines in the pathogenesis of rheumatoid arthritis (RA) seems to be unequivocal, their relationship with current serum markers of this disease is not clear. The present study analyses whether there is any correlation between the levels of tumour necrosis factor-α (TNF-α), interlukin-2 soluble receptor (sIL-2R) and the concentrations of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and β2-microglobulin in a group of 21 patients with RA, all rheumatoid factor positive.http://dx.doi.org/10.1080/0962935021000051539
collection DOAJ
language English
format Article
sources DOAJ
author Tânia Silvia Fröde
Patrícia Tenconi
Marilei Reynaud Debiasi
Yara Santos Medeiros
spellingShingle Tânia Silvia Fröde
Patrícia Tenconi
Marilei Reynaud Debiasi
Yara Santos Medeiros
Tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis
Mediators of Inflammation
author_facet Tânia Silvia Fröde
Patrícia Tenconi
Marilei Reynaud Debiasi
Yara Santos Medeiros
author_sort Tânia Silvia Fröde
title Tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis
title_short Tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis
title_full Tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis
title_fullStr Tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis
title_full_unstemmed Tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis
title_sort tumour necrosis factor-α, interleukin-2 soluble receptor and different inflammatory parameters in patients with rheumatoid arthritis
publisher Hindawi Limited
series Mediators of Inflammation
issn 0962-9351
1466-1861
publishDate 2002-01-01
description Background and aims: Although the participation of cytokines in the pathogenesis of rheumatoid arthritis (RA) seems to be unequivocal, their relationship with current serum markers of this disease is not clear. The present study analyses whether there is any correlation between the levels of tumour necrosis factor-α (TNF-α), interlukin-2 soluble receptor (sIL-2R) and the concentrations of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and β2-microglobulin in a group of 21 patients with RA, all rheumatoid factor positive.
url http://dx.doi.org/10.1080/0962935021000051539
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AT patriciatenconi tumournecrosisfactorainterleukin2solublereceptoranddifferentinflammatoryparametersinpatientswithrheumatoidarthritis
AT marileireynauddebiasi tumournecrosisfactorainterleukin2solublereceptoranddifferentinflammatoryparametersinpatientswithrheumatoidarthritis
AT yarasantosmedeiros tumournecrosisfactorainterleukin2solublereceptoranddifferentinflammatoryparametersinpatientswithrheumatoidarthritis
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