Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report

Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report

<p>Abstract</p> <p>Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with pulmonary hemorrhage is rare in childhood. Standard treatment includes corticosteroids and cyclophosphamide (CYC), which is associated with a high level of toxicity. We report a white fe...

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Main Authors: Lehman Thomas JA, Baird Emily M, Worgall Stefan
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Pediatric Rheumatology Online Journal
Online Access:http://www.ped-rheum.com/content/9/1/33
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spelling doaj-50fa32c6c4b04f0eb18f416b6f5a64052020-11-25T00:26:06ZengBMCPediatric Rheumatology Online Journal1546-00962011-10-01913310.1186/1546-0096-9-33Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case reportLehman Thomas JABaird Emily MWorgall Stefan<p>Abstract</p> <p>Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with pulmonary hemorrhage is rare in childhood. Standard treatment includes corticosteroids and cyclophosphamide (CYC), which is associated with a high level of toxicity. We report a white female with ANCA positive pulmonary hemorrhage who was treated with cyclophosphamide (CYC) and rituximab (RTX) combination therapy.</p> http://www.ped-rheum.com/content/9/1/33
collection DOAJ
language English
format Article
sources DOAJ
author Lehman Thomas JA
Baird Emily M
Worgall Stefan
spellingShingle Lehman Thomas JA
Baird Emily M
Worgall Stefan
Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report
Pediatric Rheumatology Online Journal
author_facet Lehman Thomas JA
Baird Emily M
Worgall Stefan
author_sort Lehman Thomas JA
title Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report
title_short Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report
title_full Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report
title_fullStr Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report
title_full_unstemmed Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report
title_sort combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (anca) positive pulmonary hemorrhage: case report
publisher BMC
series Pediatric Rheumatology Online Journal
issn 1546-0096
publishDate 2011-10-01
description <p>Abstract</p> <p>Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with pulmonary hemorrhage is rare in childhood. Standard treatment includes corticosteroids and cyclophosphamide (CYC), which is associated with a high level of toxicity. We report a white female with ANCA positive pulmonary hemorrhage who was treated with cyclophosphamide (CYC) and rituximab (RTX) combination therapy.</p>
url http://www.ped-rheum.com/content/9/1/33
work_keys_str_mv AT lehmanthomasja combinationtherapywithrituximabandcyclophosphamideinthetreatmentofantineutrophilcytoplasmicantibodiesancapositivepulmonaryhemorrhagecasereport
AT bairdemilym combinationtherapywithrituximabandcyclophosphamideinthetreatmentofantineutrophilcytoplasmicantibodiesancapositivepulmonaryhemorrhagecasereport
AT worgallstefan combinationtherapywithrituximabandcyclophosphamideinthetreatmentofantineutrophilcytoplasmicantibodiesancapositivepulmonaryhemorrhagecasereport
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