Staphylococcus aureus in vitro secretion of alpha toxin (hla) correlates with the affiliation to clonal complexes.

The alpha toxin of Staphylococcus aureus is a pore forming toxin that penetrates host cell membranes causing osmotic swelling, rupture, lysis and subsequently cell death. Haemolysin alpha is toxic to a wide range of different mammalian cells; i.e., neurotoxic, dermonecrotic, haemolytic, and it can c...

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Bibliographic Details
Main Authors: Stefan Monecke, Elke Müller, Joseph Büchler, Bettina Stieber, Ralf Ehricht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4062534?pdf=render