Activation of the TRAAK two-pore domain potassium channels in rd1 mice protects photoreceptor cells from apoptosis

Activation of the TRAAK two-pore domain potassium channels in rd1 mice protects photoreceptor cells from apoptosis

AIM: To investigate the expression of TWIK-related arachidonic acid-stimulated K+ channel (TRAAK) in retinal degeneration mice (rd1) and further evaluate how TRAAK affect photoreceptor cell apoptosis. METHODS: The rd1 mice were distributed into blank (no treatment), control (1.4% DMSO, intraperiton...

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Bibliographic Details
Main Authors: Lei Wang, Kang-Pei Shi, Han Li, Hao Huang, Wen-Bin Wu, Chu-Sheng Cai, Xiao-Tong Zhang, Xiao-Bo Zhu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2019-08-01
Series:International Journal of Ophthalmology
Subjects:
traak
riluzole
photoreceptor cell
apoptosis
Online Access:http://www.ijo.cn/en_publish/2019/8/20190803.pdf

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