Impact of extracorporeal shock waves on the human skin with cellulite: A case study of an unique instance

Christoph Kuhn1, Fiorenzo Angehrn1, Ortrud Sonnabend2, Axel Voss31Klinik Piano, Biel, Switzerland; 2Pathodiagnostics, Herisau, Switzerland; 3SwiTech Medical AG, Kreuzlingen, SwitzerlandAbstract: In this case study of an unique instance, effects of medium-energy, high-focused extracorporeal generated...

Full description

Bibliographic Details
Main Authors: Christoph Kuhn, Fiorenzo Angehrn, Ortrud Sonnabend, Axel Voss
Format: Article
Language:English
Published: Dove Medical Press 2008-03-01
Series:Clinical Interventions in Aging
Online Access:https://www.dovepress.com/impact-of-extracorporeal-shock-waves-on-the-human-skin-with-cellulite--peer-reviewed-article-CIA
id doaj-50e33a00d9e04a27b38a21d0cd0803b6
record_format Article
spelling doaj-50e33a00d9e04a27b38a21d0cd0803b62020-11-24T22:31:12ZengDove Medical PressClinical Interventions in Aging1178-19982008-03-01Volume 3201210238Impact of extracorporeal shock waves on the human skin with cellulite: A case study of an unique instanceChristoph KuhnFiorenzo AngehrnOrtrud SonnabendAxel VossChristoph Kuhn1, Fiorenzo Angehrn1, Ortrud Sonnabend2, Axel Voss31Klinik Piano, Biel, Switzerland; 2Pathodiagnostics, Herisau, Switzerland; 3SwiTech Medical AG, Kreuzlingen, SwitzerlandAbstract: In this case study of an unique instance, effects of medium-energy, high-focused extracorporeal generated shock waves (ESW) onto the skin and the underlying fat tissue of acellulite afflicted, 50-year-old woman were investigated. The treatment consisted of four ESW applications within 21 days. Diagnostic high-resolution ultrasound (Collagenoson) was performed before and after treatment. Directly after the last ESW application, skin samples were taken for histopathological analysis from the treated and from the contra-lateral untreated area of skin with cellulite. No damage to the treated skin tissue, in particular no mechanical destruction to the subcutaneous fat, could be demonstrated by histopathological analysis. However an astounding induction of neocollageno- and neoelastino-genesis within the scaffolding fabric of the dermis and subcutis was observed. The dermis increased in thickness as well as the scaffolding within the subcutaneous fat-tissue. Optimization of critical application parameters may turn ESW into a noninvasive cellulite therapy.Keywords: cellulite, extracellular matrix, fat tissue, high-resolution ultrasound of skin, extracorporeal shock wave, histopathology, scaffolding of subcutaneous connective tissuehttps://www.dovepress.com/impact-of-extracorporeal-shock-waves-on-the-human-skin-with-cellulite--peer-reviewed-article-CIA
collection DOAJ
language English
format Article
sources DOAJ
author Christoph Kuhn
Fiorenzo Angehrn
Ortrud Sonnabend
Axel Voss
spellingShingle Christoph Kuhn
Fiorenzo Angehrn
Ortrud Sonnabend
Axel Voss
Impact of extracorporeal shock waves on the human skin with cellulite: A case study of an unique instance
Clinical Interventions in Aging
author_facet Christoph Kuhn
Fiorenzo Angehrn
Ortrud Sonnabend
Axel Voss
author_sort Christoph Kuhn
title Impact of extracorporeal shock waves on the human skin with cellulite: A case study of an unique instance
title_short Impact of extracorporeal shock waves on the human skin with cellulite: A case study of an unique instance
title_full Impact of extracorporeal shock waves on the human skin with cellulite: A case study of an unique instance
title_fullStr Impact of extracorporeal shock waves on the human skin with cellulite: A case study of an unique instance
title_full_unstemmed Impact of extracorporeal shock waves on the human skin with cellulite: A case study of an unique instance
title_sort impact of extracorporeal shock waves on the human skin with cellulite: a case study of an unique instance
publisher Dove Medical Press
series Clinical Interventions in Aging
issn 1178-1998
publishDate 2008-03-01
description Christoph Kuhn1, Fiorenzo Angehrn1, Ortrud Sonnabend2, Axel Voss31Klinik Piano, Biel, Switzerland; 2Pathodiagnostics, Herisau, Switzerland; 3SwiTech Medical AG, Kreuzlingen, SwitzerlandAbstract: In this case study of an unique instance, effects of medium-energy, high-focused extracorporeal generated shock waves (ESW) onto the skin and the underlying fat tissue of acellulite afflicted, 50-year-old woman were investigated. The treatment consisted of four ESW applications within 21 days. Diagnostic high-resolution ultrasound (Collagenoson) was performed before and after treatment. Directly after the last ESW application, skin samples were taken for histopathological analysis from the treated and from the contra-lateral untreated area of skin with cellulite. No damage to the treated skin tissue, in particular no mechanical destruction to the subcutaneous fat, could be demonstrated by histopathological analysis. However an astounding induction of neocollageno- and neoelastino-genesis within the scaffolding fabric of the dermis and subcutis was observed. The dermis increased in thickness as well as the scaffolding within the subcutaneous fat-tissue. Optimization of critical application parameters may turn ESW into a noninvasive cellulite therapy.Keywords: cellulite, extracellular matrix, fat tissue, high-resolution ultrasound of skin, extracorporeal shock wave, histopathology, scaffolding of subcutaneous connective tissue
url https://www.dovepress.com/impact-of-extracorporeal-shock-waves-on-the-human-skin-with-cellulite--peer-reviewed-article-CIA
work_keys_str_mv AT christophkuhn impactofextracorporealshockwavesonthehumanskinwithcelluliteacasestudyofanuniqueinstance
AT fiorenzoangehrn impactofextracorporealshockwavesonthehumanskinwithcelluliteacasestudyofanuniqueinstance
AT ortrudsonnabend impactofextracorporealshockwavesonthehumanskinwithcelluliteacasestudyofanuniqueinstance
AT axelvoss impactofextracorporealshockwavesonthehumanskinwithcelluliteacasestudyofanuniqueinstance
_version_ 1725738212288102400