Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis

Abstract Obesity is a positive predictor of surgical morbidity. There are few reports of laparoscopic cholecystectomy (LC) outcomes in obese patients. This study aimed to clarify this relationship. This retrospective study included patients who underwent LC at Showa University Northern Yokohama Hosp...

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Main Authors: Yuta Enami, Takeshi Aoki, Kodai Tomioka, Tomoki Hakozaki, Takahito Hirai, Hideki Shibata, Kazuhiko Saito, Yojiro Takano, Junichi Seki, Sonoko Oae, Shoji Shimada, Kenta Nakahara, Yusuke Takehara, Shumpei Mukai, Naruhiko Sawada, Fumio Ishida, Masahiko Murakami, Shin-ei Kudo
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81963-5
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spelling doaj-50df3ed8bfc44497b0c7d82c00919df02021-01-31T16:24:45ZengNature Publishing GroupScientific Reports2045-23222021-01-011111710.1038/s41598-021-81963-5Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitisYuta Enami0Takeshi Aoki1Kodai Tomioka2Tomoki Hakozaki3Takahito Hirai4Hideki Shibata5Kazuhiko Saito6Yojiro Takano7Junichi Seki8Sonoko Oae9Shoji Shimada10Kenta Nakahara11Yusuke Takehara12Shumpei Mukai13Naruhiko Sawada14Fumio Ishida15Masahiko Murakami16Shin-ei Kudo17Digestive Disease Center, Showa University Northern Yokohama HospitalDepartment of Gastrointestinal and General Surgery, Showa University, School of MedicineDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDigestive Disease Center, Showa University Northern Yokohama HospitalDepartment of Gastrointestinal and General Surgery, Showa University, School of MedicineDigestive Disease Center, Showa University Northern Yokohama HospitalAbstract Obesity is a positive predictor of surgical morbidity. There are few reports of laparoscopic cholecystectomy (LC) outcomes in obese patients. This study aimed to clarify this relationship. This retrospective study included patients who underwent LC at Showa University Northern Yokohama Hospital between January 2017 and April 2020. A total of 563 cases were examined and divided into two groups: obese (n = 142) (BMI ≥ 25 kg/m2) and non-obese (n = 241) (BMI < 25 kg/m2). The non-obese group had more female patients (54%), whereas the obese group had more male patients (59.1%). The obese group was younger (56.6 years). Preoperative laboratory data of liver function were within the normal range. The obese group had a significantly higher white blood cell (WBC) count (6420/μL), although this was within normal range. Operative time was significantly longer in the obese group (p = 0.0001). However, blood loss and conversion rate were not significantly different among the groups, neither were surgical outcomes, including postoperative hospital stay and complications. Male sex and previous abdominal surgery were risk factors for conversion, and only advanced age (≥ 79 years) was an independent predictor of postoperative complications as observed in the multivariate analysis. Although the operation time was prolonged in obese patients, operative factors and outcomes were not. Therefore, LC could be safely performed in obese patients with similar efficacy as in non-obese patients.https://doi.org/10.1038/s41598-021-81963-5
collection DOAJ
language English
format Article
sources DOAJ
author Yuta Enami
Takeshi Aoki
Kodai Tomioka
Tomoki Hakozaki
Takahito Hirai
Hideki Shibata
Kazuhiko Saito
Yojiro Takano
Junichi Seki
Sonoko Oae
Shoji Shimada
Kenta Nakahara
Yusuke Takehara
Shumpei Mukai
Naruhiko Sawada
Fumio Ishida
Masahiko Murakami
Shin-ei Kudo
spellingShingle Yuta Enami
Takeshi Aoki
Kodai Tomioka
Tomoki Hakozaki
Takahito Hirai
Hideki Shibata
Kazuhiko Saito
Yojiro Takano
Junichi Seki
Sonoko Oae
Shoji Shimada
Kenta Nakahara
Yusuke Takehara
Shumpei Mukai
Naruhiko Sawada
Fumio Ishida
Masahiko Murakami
Shin-ei Kudo
Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis
Scientific Reports
author_facet Yuta Enami
Takeshi Aoki
Kodai Tomioka
Tomoki Hakozaki
Takahito Hirai
Hideki Shibata
Kazuhiko Saito
Yojiro Takano
Junichi Seki
Sonoko Oae
Shoji Shimada
Kenta Nakahara
Yusuke Takehara
Shumpei Mukai
Naruhiko Sawada
Fumio Ishida
Masahiko Murakami
Shin-ei Kudo
author_sort Yuta Enami
title Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis
title_short Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis
title_full Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis
title_fullStr Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis
title_full_unstemmed Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis
title_sort obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-01-01
description Abstract Obesity is a positive predictor of surgical morbidity. There are few reports of laparoscopic cholecystectomy (LC) outcomes in obese patients. This study aimed to clarify this relationship. This retrospective study included patients who underwent LC at Showa University Northern Yokohama Hospital between January 2017 and April 2020. A total of 563 cases were examined and divided into two groups: obese (n = 142) (BMI ≥ 25 kg/m2) and non-obese (n = 241) (BMI < 25 kg/m2). The non-obese group had more female patients (54%), whereas the obese group had more male patients (59.1%). The obese group was younger (56.6 years). Preoperative laboratory data of liver function were within the normal range. The obese group had a significantly higher white blood cell (WBC) count (6420/μL), although this was within normal range. Operative time was significantly longer in the obese group (p = 0.0001). However, blood loss and conversion rate were not significantly different among the groups, neither were surgical outcomes, including postoperative hospital stay and complications. Male sex and previous abdominal surgery were risk factors for conversion, and only advanced age (≥ 79 years) was an independent predictor of postoperative complications as observed in the multivariate analysis. Although the operation time was prolonged in obese patients, operative factors and outcomes were not. Therefore, LC could be safely performed in obese patients with similar efficacy as in non-obese patients.
url https://doi.org/10.1038/s41598-021-81963-5
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