Bioactive Bis(indole) Alkaloids from a Spongosorites sp. Sponge

Bioactive Bis(indole) Alkaloids from a Spongosorites sp. Sponge

Six new bis(indole) alkaloids (1–6) along with eight known ones of the topsentin class were isolated from a Spongosorites sp. sponge of Korea. Based on the results of combined spectroscopic analyses, the structures of spongosoritins A–D (1–4) were determined to possess a 2-methoxy-1-imidazole-5-one...

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Bibliographic Details
Main Authors: Jae Sung Park, Eunji Cho, Ji-Yeon Hwang, Sung Chul Park, Beomkoo Chung, Oh-Seok Kwon, Chung J. Sim, Dong-Chan Oh, Ki-Bong Oh, Jongheon Shin
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Marine Drugs
Subjects:
Spongosorites sp. sponge
bis(indole) alkaloids
spongosoritins
spongocarbamides
topsentin
sortase A inhibition
Online Access:https://www.mdpi.com/1660-3397/19/1/3

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