ANALYSIS OF DOMAIN SPECIFICITY OF THE PROTECTIVE CHIMERIC ANTIBODY ch14D5a AGAINST GLYCOPROTEIN E OF TICK-BORNE ENCEPHALITIS VIRUS

ANALYSIS OF DOMAIN SPECIFICITY OF THE PROTECTIVE CHIMERIC ANTIBODY ch14D5a AGAINST GLYCOPROTEIN E OF TICK-BORNE ENCEPHALITIS VIRUS

A drug for the prevention and therapy of tick-borne encephalitis virus is being developed on the basis of the protective chimeric antibody ch14D5a. At the same time, the epitope recognized by this antibody on the surface of glycoprotein E has not been localized yet. The aim of this work was to ident...

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Bibliographic Details
Main Authors: I. K. Baykov, L. A. Emelyanova, L. M. Sokolova, E. M. Karelina, A. L. Matveev, I. V. Babkin, Ya. А. Khlusevich, V. F. Podgornyy, N. V. Tikunova
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2018-07-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
tick-borne encephalitis virus
glycoprotein e
domain d3
antibody
recombinant protein
surface plasmon resonance
epitope mapping
Online Access:https://vavilov.elpub.ru/jour/article/view/1550

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