Cumulative number of cell divisions as a meaningful timescale for adaptive laboratory evolution of Escherichia coli.

Adaptive laboratory evolution (ALE) under controlled conditions has become a valuable approach for the study of the genetic and biochemical basis for microbial adaptation under a given selection pressure. Conventionally, the timescale in ALE experiments has been set in terms of number of generations...

Full description

Bibliographic Details
Main Authors: Dae-Hee Lee, Adam M Feist, Christian L Barrett, Bernhard Ø Palsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3196513?pdf=render