Signals from the Niche: Insights into the Role of IGF-1 and IL-6 in Modulating Skeletal Muscle Fibrosis

Muscle regeneration, characterized by the activation and proliferation of satellite cells and other precursors, is accompanied by an inflammatory response and the remodeling of the extracellular matrix (ECM), necessary to remove cellular debris and to mechanically support newly generated myofibers a...

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Bibliographic Details
Main Authors: Laura Forcina, Carmen Miano, Bianca Maria Scicchitano, Antonio Musarò
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/8/3/232