The Effects of High Molecular Weight Hyaluronic Acid Eye Drop Application in Environmental Dry Eye Stress Model Mice

The Effects of High Molecular Weight Hyaluronic Acid Eye Drop Application in Environmental Dry Eye Stress Model Mice

Hyaluronic acid (HA) ophthalmic solution is widely used in dry eye treatment worldwide. However, there are no reports comparing the dry eye treatment effects of high molecular weight HA with low molecular weight HA. Sixty eight-week-old C57BL/6 mice were assigned to the following 6 groups and expose...

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Bibliographic Details
Main Authors: Takashi Kojima, Taeko Nagata, Haruka Kudo, Wolfgang G. K. Müller-Lierheim, Gysbert-Botho van Setten, Murat Dogru, Kazuo Tsubota
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
dry eye
high molecular weight hyaluronic acid
treatment
corneal subbasal dendritic cell density
Muc5AC
ocular surface staining
Online Access:https://www.mdpi.com/1422-0067/21/10/3516

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