Formulation and evaluation of bi-layer floating tablets of ziprasidone HCl and trihexyphenidyl HCl

Formulation and evaluation of bi-layer floating tablets of ziprasidone HCl and trihexyphenidyl HCl

The purpose of this research study was to establish ziprasidone HCl NR 40 mg and trihexyphenidyl HCl SR 4mg in the form of bi-layer sustained release floating tablets. The tablets were prepared using sodium HPMC K4M / HPMC K15M as bio-adhesive polymers and sodium bicarbonate acting as a floating lay...

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Bibliographic Details
Main Authors: Sathis Kumar Dinakaran, Santhos Kumar, David Banji, Harani Avasarala, Venkateshwar Rao
Format: Article
Language:English
Published: Universidade de São Paulo 2011-09-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Comprimidos bicamada
Ziprasidona.HCl.
Triexifenidila.HCl.
Liberação controlada
Bi-layer tablet
Ziprasidone HCl
Trihexyphenidyl HCl
Sustained release
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300012

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