Synthesis and Adrenolytic Activity of New Propanolamines

Synthesis and Adrenolytic Activity of New Propanolamines

The synthesis of (2R,S)-1-(6-methoxy-4-(methoxymethyl)-1H-indol-5-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol and (2R,S)-1-(4-methoxy-6-(methoxymethyl)-1H-indol-5-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol is described. The compounds were tested for electrographic, antiarrhythmic,...

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Bibliographic Details
Main Authors: Grażyna Groszek, Agata Bajek, Agnieszka Bis, Agnieszka Nowak-Król, Marek Bednarski, Agata Siwek, Barbara Filipek
Format: Article
Language:English
Published: MDPI AG 2010-05-01
Series:Molecules
Subjects:
α1-andrenoceptor antagonist
synthesis
pharmacology
Online Access:http://www.mdpi.com/1420-3049/15/6/3887/

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