Considerations and Caveats in Combating ESKAPE Pathogens against Nosocomial Infections

Considerations and Caveats in Combating ESKAPE Pathogens against Nosocomial Infections

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Abstract ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) are among the most common opportunistic pathogens in nosocomial infections. ESKAPE pathogens distinguish themselves from normal on...

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Bibliographic Details
Main Authors: Yu‐Xuan Ma, Chen‐Yu Wang, Yuan‐Yuan Li, Jing Li, Qian‐Qian Wan, Ji‐Hua Chen, Franklin R. Tay, Li‐Na Niu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Advanced Science
Subjects:
antimicrobial peptides
antiresistance
antivirulence
bacteriophages
nanodelivery strategies
Online Access:https://doi.org/10.1002/advs.201901872
Description
Summary:Abstract ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) are among the most common opportunistic pathogens in nosocomial infections. ESKAPE pathogens distinguish themselves from normal ones by developing a high level of antibiotic resistance that involves multiple mechanisms. Contemporary therapeutic strategies which are potential options in combating ESKAPE bacteria need further investigation. Herein, a broad overview of the antimicrobial research on ESKAPE pathogens over the past five years is provided with prospective clinical applications.
ISSN:2198-3844

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