3D host cell and pathogen-based bioassay development for testing anti-tuberculosis (TB) drug response and modeling immunodeficiency

3D host cell and pathogen-based bioassay development for testing anti-tuberculosis (TB) drug response and modeling immunodeficiency

Tuberculosis (TB) is a global health threat that affects 10 million people worldwide. Human Immunodeficiency Virus (HIV) remains one of the major contributors to the reactivation of asymptomatic latent tuberculosis (LTBI). Over the recent years, there has been a significant focus in developing in-vi...

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Bibliographic Details
Main Authors: Mukundan Shilpaa, Bhatt Rachana, Lucas John, Tereyek Matthew, Chang Theresa L., Subbian Selvakumar, Parekkadan Biju
Format: Article
Language:English
Published: De Gruyter 2021-09-01
Series:Biomolecular Concepts
Subjects:
bioassay
tuberculosis
drug response
human immunodeficiency virus
hiv-tb co-infection
granuloma
anti-tuberculosis drugs
Online Access:https://doi.org/10.1515/bmc-2021-0013

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