Integrated molecular characterization of adult soft tissue sarcoma for therapeutic targets

Integrated molecular characterization of adult soft tissue sarcoma for therapeutic targets

Abstract Background Several studies have investigated the molecular drivers and therapeutic targets in adult soft tissue sarcomas. However, such studies are limited by the genomic heterogeneity and rarity of sarcomas, particularly in those with complex and unbalanced karyotypes. Additional biomarker...

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Bibliographic Details
Main Authors: Jihyun Kim, June Hyuk Kim, Hyun Guy Kang, Seog Yun Park, Jung Yeon Yu, Eun Young Lee, Sung Eun Oh, Young Ho Kim, Tak Yun, Charny Park, Soo Young Cho, Hye Jin You
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Medical Genetics
Subjects:
Complex karyotype sarcoma
Molecular characterization
PDGFRA
CDK4 and RB1
Online Access:http://link.springer.com/article/10.1186/s12881-018-0722-6

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