CTLA-4 correlates with immune and clinical characteristics of glioma

Abstract Background CTLA-4 is a well-studied immune checkpoint protein that negatively regulates T cell-mediated immune responses. However, the expression of CTLA-4 in glioma and the effects of CTLA-4 on prognosis in patients with glioma have not yet been examined. Methods We investigated the protei...

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Bibliographic Details
Main Authors: Fangkun Liu, Jing Huang, Xuming Liu, Quan Cheng, Chengke Luo, Zhixiong Liu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-019-1085-6