New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.
Two new ent-kaurane diterpene glycosides, ranunculosides A (1) and B (2), and a new benzophenone, ranunculone C (3), were isolated from the aerial part of Ranunculus muricatus Linn. The chemical structures of compounds 1–3 were established to be (2S)-ent-kauran-2β-ol-15-en-14-O-β-d-glucopyranoside,...
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| Language: | English |
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MDPI AG
2015-12-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/20/12/19801 |
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doaj-50778370c71c4f39b98e0032479b47662020-11-25T00:00:47ZengMDPI AGMolecules1420-30492015-12-012012224452245310.3390/molecules201219801molecules201219801New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn.Bi-Ling Wu0Hui-Liang Zou1Fang-Min Qin2Hong-Yu Li3Guang-Xiong Zhou4Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy Jinan University, Guangzhou 510632, ChinaGuangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy Jinan University, Guangzhou 510632, ChinaGuangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy Jinan University, Guangzhou 510632, ChinaGuangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy Jinan University, Guangzhou 510632, ChinaGuangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy Jinan University, Guangzhou 510632, ChinaTwo new ent-kaurane diterpene glycosides, ranunculosides A (1) and B (2), and a new benzophenone, ranunculone C (3), were isolated from the aerial part of Ranunculus muricatus Linn. The chemical structures of compounds 1–3 were established to be (2S)-ent-kauran-2β-ol-15-en-14-O-β-d-glucopyranoside, (2S,4S)-ent-kauran-2β,18-diol-15-en-14-O-β-d-glucopyranoside, and (R)-3-[2-(3,4-dihydroxybenzoyl)-4,5-dihydroxy-phenyl]-2-hydroxylpropanoic acid, respectively, by spectroscopic data and chemical methods. The absolute configuration of 1 was determined by the combinational application of RP-HPLC analysis and Mosher’s method.http://www.mdpi.com/1420-3049/20/12/19801Ranunculus muricatusent-kaurane diterpeneranunculosidebenzophenoneranunculone C |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Bi-Ling Wu Hui-Liang Zou Fang-Min Qin Hong-Yu Li Guang-Xiong Zhou |
| spellingShingle |
Bi-Ling Wu Hui-Liang Zou Fang-Min Qin Hong-Yu Li Guang-Xiong Zhou New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn. Molecules Ranunculus muricatus ent-kaurane diterpene ranunculoside benzophenone ranunculone C |
| author_facet |
Bi-Ling Wu Hui-Liang Zou Fang-Min Qin Hong-Yu Li Guang-Xiong Zhou |
| author_sort |
Bi-Ling Wu |
| title |
New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn. |
| title_short |
New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn. |
| title_full |
New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn. |
| title_fullStr |
New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn. |
| title_full_unstemmed |
New Ent-Kaurane-Type Diterpene Glycosides and Benzophenone from Ranunculus muricatus Linn. |
| title_sort |
new ent-kaurane-type diterpene glycosides and benzophenone from ranunculus muricatus linn. |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2015-12-01 |
| description |
Two new ent-kaurane diterpene glycosides, ranunculosides A (1) and B (2), and a new benzophenone, ranunculone C (3), were isolated from the aerial part of Ranunculus muricatus Linn. The chemical structures of compounds 1–3 were established to be (2S)-ent-kauran-2β-ol-15-en-14-O-β-d-glucopyranoside, (2S,4S)-ent-kauran-2β,18-diol-15-en-14-O-β-d-glucopyranoside, and (R)-3-[2-(3,4-dihydroxybenzoyl)-4,5-dihydroxy-phenyl]-2-hydroxylpropanoic acid, respectively, by spectroscopic data and chemical methods. The absolute configuration of 1 was determined by the combinational application of RP-HPLC analysis and Mosher’s method. |
| topic |
Ranunculus muricatus ent-kaurane diterpene ranunculoside benzophenone ranunculone C |
| url |
http://www.mdpi.com/1420-3049/20/12/19801 |
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