Intra-Arterially Delivered Mesenchymal Stem Cells Are Not Detected in the Brain Parenchyma in an Alzheimer's Disease Mouse Model.

Mesenchymal stem cells (MSCs) have a promising role as a therapeutic agent for neurodegenerative diseases such as Alzheimer's disease (AD). Prior studies suggested that intra-arterially administered MSCs are engrafted into the brain in stroke or traumatic brain injury (TBI) animal models. Howev...

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Bibliographic Details
Main Authors: Na Kyung Lee, Jehoon Yang, Eun Hyuk Chang, Sang Eon Park, Jeongmin Lee, Soo Jin Choi, Wonil Oh, Jong Wook Chang, Duk L Na
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4874686?pdf=render