Evaluation of metabolic syndrome in adults of Talca city, Chile

<p>Abstract</p> <p>Objective-</p> <p>Insulin resistance (IR) is an important risk factor for type 2 Diabetes Mellitus (DM2) and cardiovascular disease (CVD). Metabolic Syndrome (MS) is a clustering of metabolic alterations associated to IR; however, there is no internat...

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Main Authors: Moore-Carrasco Rodrigo, Arredondo Miguel, Diaz Nora, Icaza Gloria, Leiva Elba, Mujica Veronica, Orrego Roxana, Vásquez Marcela, Palomo Ivan
Format: Article
Language:English
Published: BMC 2008-05-01
Series:Nutrition Journal
Online Access:http://www.nutritionj.com/content/7/1/14
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spelling doaj-5065ad0cadd84054a6d01f3c39fa8d032020-11-24T20:48:13ZengBMCNutrition Journal1475-28912008-05-01711410.1186/1475-2891-7-14Evaluation of metabolic syndrome in adults of Talca city, ChileMoore-Carrasco RodrigoArredondo MiguelDiaz NoraIcaza GloriaLeiva ElbaMujica VeronicaOrrego RoxanaVásquez MarcelaPalomo Ivan<p>Abstract</p> <p>Objective-</p> <p>Insulin resistance (IR) is an important risk factor for type 2 Diabetes Mellitus (DM2) and cardiovascular disease (CVD). Metabolic Syndrome (MS) is a clustering of metabolic alterations associated to IR; however, there is no international consensus for defining its diagnosis. Our objective was to evaluate the prevalence and characteristics of MS identified by the ATP III and IDF criteria in adults from Talca city.</p> <p>Research and methods-</p> <p>We studied 1007 individuals, aged 18–74, and residents from Talca. MS subjects were defined according to ATP III (three altered factors) and IDF criteria (patients with waist circumference >80/90 cm (W/M) and two others altered factors).</p> <p>Results-</p> <p>The prevalence of metabolic syndrome according to the IDF and ATP III criteria was 36.4% and 29.5%, respectively after adjustment for age and sex. The agreement for both criteria was 89%. The prevalence in men was higher than in women for both MS definitions, although not significant. MS probability increased with age, and the highest risk was in the 57–68 age group (ATP-MS) and 53–72 age group (IDF-MS). Hypertension, high triglycerides and abdominal obesity are the most frequent alterations in MS.</p> <p>Conclusion-</p> <p>MS prevalence in adults was higher when diagnosed with IDF than with ATP criterion; in both, age is directly related with the MS presence. The MS subjects showed higher levels of blood pressure, waist circumference and plasma triglycerides. Considering our results, it is worrisome that one third of our population has a high risk of developing DM2 and CVD in the future.</p> http://www.nutritionj.com/content/7/1/14
collection DOAJ
language English
format Article
sources DOAJ
author Moore-Carrasco Rodrigo
Arredondo Miguel
Diaz Nora
Icaza Gloria
Leiva Elba
Mujica Veronica
Orrego Roxana
Vásquez Marcela
Palomo Ivan
spellingShingle Moore-Carrasco Rodrigo
Arredondo Miguel
Diaz Nora
Icaza Gloria
Leiva Elba
Mujica Veronica
Orrego Roxana
Vásquez Marcela
Palomo Ivan
Evaluation of metabolic syndrome in adults of Talca city, Chile
Nutrition Journal
author_facet Moore-Carrasco Rodrigo
Arredondo Miguel
Diaz Nora
Icaza Gloria
Leiva Elba
Mujica Veronica
Orrego Roxana
Vásquez Marcela
Palomo Ivan
author_sort Moore-Carrasco Rodrigo
title Evaluation of metabolic syndrome in adults of Talca city, Chile
title_short Evaluation of metabolic syndrome in adults of Talca city, Chile
title_full Evaluation of metabolic syndrome in adults of Talca city, Chile
title_fullStr Evaluation of metabolic syndrome in adults of Talca city, Chile
title_full_unstemmed Evaluation of metabolic syndrome in adults of Talca city, Chile
title_sort evaluation of metabolic syndrome in adults of talca city, chile
publisher BMC
series Nutrition Journal
issn 1475-2891
publishDate 2008-05-01
description <p>Abstract</p> <p>Objective-</p> <p>Insulin resistance (IR) is an important risk factor for type 2 Diabetes Mellitus (DM2) and cardiovascular disease (CVD). Metabolic Syndrome (MS) is a clustering of metabolic alterations associated to IR; however, there is no international consensus for defining its diagnosis. Our objective was to evaluate the prevalence and characteristics of MS identified by the ATP III and IDF criteria in adults from Talca city.</p> <p>Research and methods-</p> <p>We studied 1007 individuals, aged 18–74, and residents from Talca. MS subjects were defined according to ATP III (three altered factors) and IDF criteria (patients with waist circumference >80/90 cm (W/M) and two others altered factors).</p> <p>Results-</p> <p>The prevalence of metabolic syndrome according to the IDF and ATP III criteria was 36.4% and 29.5%, respectively after adjustment for age and sex. The agreement for both criteria was 89%. The prevalence in men was higher than in women for both MS definitions, although not significant. MS probability increased with age, and the highest risk was in the 57–68 age group (ATP-MS) and 53–72 age group (IDF-MS). Hypertension, high triglycerides and abdominal obesity are the most frequent alterations in MS.</p> <p>Conclusion-</p> <p>MS prevalence in adults was higher when diagnosed with IDF than with ATP criterion; in both, age is directly related with the MS presence. The MS subjects showed higher levels of blood pressure, waist circumference and plasma triglycerides. Considering our results, it is worrisome that one third of our population has a high risk of developing DM2 and CVD in the future.</p>
url http://www.nutritionj.com/content/7/1/14
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