Phytochemistry, Pharmacology and Traditional Uses of Plants from the Genus Trachelospermum L.

• Main Authors: Zefeng Zhao, Xirui He, Yuhui Zhao, Ying Sun, Xufei Chen, Ye Cun, Linhong Huang, Yajun Bai, Xiaohui Zheng
• Format: Article
• Language: English
• Published: MDPI AG 2017-08-01
• Series: Molecules
• Subjects: Trachelospermum; lignans; anti-inflammatory; analgesic; antitumor; review
• Online Access: https://www.mdpi.com/1420-3049/22/9/1406

This paper is intended to review advances in the botanical, phytochemical, traditional uses and pharmacological studies of the genus Trachelospermum. Until now, 138 chemical constituents have been isolated and characterized from these plants, particularly from T. asiaticum and T. jasminoides. Among these compounds, lignans, triterpenoids, and flavonoids are the major bioactive constituents. Studies have shown that plants from the genus Trachelospermum exhibit an extensive range of pharmacological properties both in vivo and in vitro, including anti-inflammatory, analgesic, antitumor, antiviral and antibacterial activities. In Traditional Chinese Medicine (TCM) culture, drugs that include T. jasminoides stems have been used to cure rheumatism, gonarthritis, backache and pharyngitis, although there are few reports concerning the clinical use and toxicity of these plants. Further attention should be paid to gathering information about their toxicology data, quality-control measures, and the clinical value of the active compounds from genus Trachelospermum.