Impact and Relevance of the Unfolded Protein Response in HNSCC

Impact and Relevance of the Unfolded Protein Response in HNSCC

Head and neck squamous cell carcinomas (HNSCC) encompass a heterogeneous group of solid tumors that arise from the upper aerodigestive tract. The tumor cells face multiple challenges including an acute demand of protein synthesis often driven by oncogene activation, limited nutrient and oxygen suppl...

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Bibliographic Details
Main Authors:	Olivier Pluquet, Antoine Galmiche
Format:	Article
Language:	English
Published:	MDPI AG 2019-05-01
Series:	International Journal of Molecular Sciences
Subjects:	Head and Neck Squamous Cell Carcinoma (HNSCC) Unfolded Protein Response (UPR) therapy biomarkers prognosis
Online Access:	https://www.mdpi.com/1422-0067/20/11/2654

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