Liver Fibrosis in HCV Monoinfected and HIV/HCV Coinfected Patients: Dysregulation of Matrix Metalloproteinases (MMPs) and Their Tissue Inhibitors TIMPs and Effect of HCV Protease Inhibitors

Liver Fibrosis in HCV Monoinfected and HIV/HCV Coinfected Patients: Dysregulation of Matrix Metalloproteinases (MMPs) and Their Tissue Inhibitors TIMPs and Effect of HCV Protease Inhibitors

An imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) may contribute to liver fibrosis in patients with hepatitis C (HCV) infection. We measured the circulating levels of different MMPs and TIMPs in HCV monoinfected and HIV/HCV coinfected patients...

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Bibliographic Details
Main Authors: Tiziana Latronico, Claudia Mascia, Ilaria Pati, Paola Zuccala, Fabio Mengoni, Raffaella Marocco, Tiziana Tieghi, Valeria Belvisi, Miriam Lichtner, Vincenzo Vullo, Claudio Maria Mastroianni, Grazia Maria Liuzzi
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:International Journal of Molecular Sciences
Subjects:
matrix metalloproteinases
tissue inhibitors of metalloproteinases
HIV/HCV coinfection
liver fibrosis
anti-HCV therapy
Online Access:http://www.mdpi.com/1422-0067/17/4/455

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