Spectroscopic screening of pancreatic cancer

Spectroscopic screening of pancreatic cancer

Pancreatic cancer is one of the most aggressive and lethal malignant neoplasms in the world and 5-year survival rate still remains below 10%. Although, there are many reasons for that, one definitely is the lack of early and unique diagnostic tools for pancreatic cancer screening, which somehow corr...

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Bibliographic Details
Main Authors: Krzysztof Szymoński, Ewelina Lipiec, Kamila Sofińska, Katarzyna Skirlińska-Nosek, Katarzyna Milian-Ciesielska, Joanna Szpor, Michał Czaja, Sara Seweryn, Natalia Wilkosz, Giovanni Birarda, Federica Piccirilli, Lisa Vaccari, Marek Szymoński
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Clinical Spectroscopy
Subjects:
Pancreatic cancer
Raman spectroscopy
FTIR
Ampullary
Carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2666054721000119
Description
Summary:Pancreatic cancer is one of the most aggressive and lethal malignant neoplasms in the world and 5-year survival rate still remains below 10%. Although, there are many reasons for that, one definitely is the lack of early and unique diagnostic tools for pancreatic cancer screening, which somehow correlates with no sufficient knowledge about cancer’s molecular nature. This article aims to prove the concept that an application of molecular spectroscopic methods including FTIR hyperspectral imaging and Raman hyperspectral mapping, combined with proper tissue pre-processing and analytical algorithms, allows differentiating benign and malignant pancreatic glands with good precision.
ISSN:2666-0547

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