Inhibition of SOC/Ca<sup>2+</sup>/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells

Inhibition of SOC/Ca<sup>2+</sup>/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells

<p>Abstract</p> <p>Background</p> <p>Sildenafil, a potent phosphodiesterase type 5 (PDE5) inhibitor, has been proposed as a treatment for pulmonary arterial hypertension (PAH). The mechanism of its anti-proliferative effect on pulmonary artery smooth muscle cells (PASMC...

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Bibliographic Details
Main Authors:	Liu Jie, Zhao Lan, Li Ji-Feng, Wang Cong, Wan Jun, Wang Yue, Wang Jun, Wang Chen
Format:	Article
Language:	English
Published:	BMC 2009-12-01
Series:	Respiratory Research
Online Access:	http://respiratory-research.com/content/10/1/123

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