Enoxaparin is a low-molecular-weight heparin with a complex chemical structure and various non-anticoagulant properties

The paper discusses the non-anticoagulant properties of unfractionated heparin and enoxaparin and their relation to their chemical structures. It is emphasized that enoxaparin has multiple, often interrelated, non-anticoagulant effects that can complement its antithrombotic activity and enhance the...

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Bibliographic Details
Main Authors: S K Zyryanov, E A Ushkalova
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2016-12-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/32121/pdf
Description
Summary:The paper discusses the non-anticoagulant properties of unfractionated heparin and enoxaparin and their relation to their chemical structures. It is emphasized that enoxaparin has multiple, often interrelated, non-anticoagulant effects that can complement its antithrombotic activity and enhance the efficiency of therapy in patients receiving the drug for various indications. The realization of these effects requires the complex structure with the standard distribution of molecular weight (Mw) (average Mw, about 4500 Da, as well as Mw of less than 2000 Da (68%), and more than 8000 Da (
ISSN:0040-3660
2309-5342